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Canadian doctors who found weak case for 'gender intervention' bow to activists

Under activist pressure, McMaster University - the birthplace of evidence-based medicine - has issued a statement rejecting its own standards for fact-based science.

Melanie Bennet, True North.
Aug 22, 2025
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McMaster University, the birthplace of evidence-based medicine, has issued a statement rejecting its own standards for fact-based science. Dr. Gordon Guyatt, the physician who pioneered evidence-based medicine and co-developed the GRADE (Grading of Recommendations, Assessment, Development and Evaluation) system used worldwide to assess the strength of clinical research, recently co-authored systematic reviews of gender-affirming care. Those reviews concluded that “only low certainty evidence exists” for the benefits of intervention.

Guyatt and four colleagues authored systematic reviews of gender-affirming interventions, funded by the Society for Evidence-Based Gender Medicine. Those reviews concluded that the evidence for benefits of gender affirming care was of “low certainty.”

The Society for Evidence-Based Gender Medicine has long faced heavy criticism, accusing them of coordinating anti-trans lobbying efforts that undermine gender‑affirming care. Trans activists have repeatedly demanded that health care practitioners reject their scientific findings.

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